Dr. Berne’s Omega 3 Formula is a high-potency omega-3 product providing 600 mg of eicosapentaenoic acid (EPA) and 400 mg of dexahexapentaeonic acid (DHA) in each 2-softgel serving. This product may be an ideal choice when a more aggressive application of omega-3 is desired.
In order to maintain optimum health, the body requires a variety of different fats. Two of these—omega-6 and omega-3 fatty acids—are essential. As a result of industrialized farming practices and modern food processing technology, the American diet is very high in omega-6s, but low in omega-3s. Correcting this imbalance through foods and supplements can be beneficial for the entire body.
The Story Behind Omega-3s
The best sources of omega-3 fats are cold water fish like salmon, sardines, and mackerel. The omega-3s that come from marine animals are different from the plant forms (such as walnuts and flaxseed), in that many people cannot effectively convert the plant forms to the animal forms, which are the more potent and biologically active versions that the body ultimately requires.
Since most people do not consume cold water fish regularly, supplementation is critical for those concerned about any of the health issues listed to the right, and is also recommended for healthy individuals in order to maintain a good baseline balance of fatty acids.
Proper fatty acid ratios help support:
- Healthy joints
- Robust immune function
- Hydrated skin and lustrous, shiny hair
- Cardiovascular health
• Positive mental outlook and balanced moods
- Clear thinking, memory, and cognitive function
- Healthy cell membranes
Dr. Berne’s Omega 3 Formula contains the omega-3 fatty acids EPA & DHA:
- Eicosapentaenoic acid (EPA) – beneficial for supporting a healthy brain, balanced emotions, skin health, maintaining normal cholesterol levels and modulating the inflammatory response*
- Docosahexaenoic acid (DHA) – supports proper brain development and function, visual acuity, maintenance of normal triglyceride levels and blood pressure, eye development and a healthy pregnancy in expectant moms*
Dr. Berne’s Omega 3 Formula contains fish oils in the triglyceride (TG) form —the same way they naturally occur in fish. Most mass-marketed and lower-priced fish oil supplements come in the ethylester (EE) form. These are less expensive and more convenient to produce, but they are not as readily recognized, digested, and assimilated in the body as the TG form. In order to receive the maximum benefit from omega-3 supplementation, it is critical to provide these fats to the body in the same way they are found naturally in fish. It is only when consumed in this natural form that they are most easily digested and absorbed.
Purity – Dr. Berne’s Omega 3 Formula also includes mixed tocopherols, which protect these fragile oils from oxidation and rancidity. Additionally, these fish oils are molecularly distilled and filtered to ensure purity and to maximize the removal of metals, pesticides, PCBs, and other contaminants.
Recommended Use: Take 2 softgels per day with meals or as directed by your health-care practitioner.
Warning: Consult your health-care practitioner before use if you are taking blood thinner medication or if you are planning to have surgery.
ALL SALES ARE FINAL. SORRY NO RETURNS OR REFUNDS
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Dr. Berne’s Omega 3 Formula is a blend of high potency omega-3 essential fatty acids (FAs), providing 600 mg EPA, 400 mg DHA, and 200 mg other omega-3 fatty acids from fish oils in each two softgel serving, along with the digestive aid lipase for enhanced lipid absorption. This product may be an ideal choice when more aggressive applications of omega-3s are desired. Every cell in the body requires FAs to function properly and maintain optimum health, as they are necessary in the process of rebuilding and synthesizing new cells. Two of these fatty acids—omega-6 and omega-3 fatty acids—are essential since they cannot be synthesized by the body. As a result of industrialized farming practices and modern food processing technology, the American diet is very high in omega-6 FAs but low in omega-3s. Correcting this imbalance through foods and supplements can be beneficial for the entire body. FAs have a desirable effect on many conditions; they support heart health, normal cholesterol and triglyceride levels, immune system function, brain and nervous system health, joint mobility, healthy skin and hair, and healthy modulation of the inflammatory response.1-3
The omega-3 (n-3) fatty acids in this formula are derived from fish oils in their natural triglyceride (TG) form – the same way they naturally occur in fish. Most mass-marketed fish oil supplements come in the synthetic ethyl ester (EE) form. Compared to the TG form, the EE form is more convenient to produce but not as readily recognized, digested, and assimilated by the body, and is more prone to oxidation and production of free radicals. To receive the maximum benefits from n-3 fish oil supplementation, it is critical that these fats are provided in the most bioavailable and bioidentical form, the same form that is naturally found in fish and in the tissues of the human body. The TG form is broken down 12-15% faster than the EE form by pancreatic lipase enzyme, which is also included in this formula for enhanced digestion and absorption of fish oils. Because the natural TG form is most easily digested and available for the body to use, this TruTGTM advantage is effective at promoting healthy n-3 levels in the body.
The Story Behind Omega-3s
The best sources of omega-3 fats are cold-water, wild-caught fish like sockeye salmon, sardines, and mackerel. The omega-3s that come from marine animals are different from the plant forms (such as walnuts and flaxseed), in that many people cannot effectively convert the plant forms to the animal forms, which are the more potent and biologically active versions that the body ultimately requires. Omega-3 essential FAs have been shown to create more stable arterial plaque benefiting heart health compared to the omega-6 fatty acids that are derived from unsaturated vegetable oils such as soybean, corn, sunflower, and cottonseed oils.1,4 Since most people do not consume cold-water fish regularly, supplementation is critical for those concerned about any of the health issues listed below, and is also recommended for healthy individuals in order to maintain optimum fatty acid ratios.
EPA & DHA
Eicosapentaenoic acid (EPA) is beneficial for supporting healthy brain function, balanced emotions, skin health, normal cholesterol levels, and a proper inflammatory response.5-8 Docosahexaenoic acid (DHA) supports proper brain development and function, visual acuity, maintenance of normal triglyceride levels and blood pressure, eye development, and a healthy pregnancy for expectant mothers.9-13
A meta-analysis showed that EPA and DHA supplementation reduced serum triglycerides and raised high-density lipoprotein (HDL) cholesterol.14 In patients with hypertriglyceridemia taking a statin, 4 g/d of EPA significantly reduced the incidence of major cardiovascular events, suggesting cardioprotective effects.15,16 Moreover, n-3 polyunsaturated fatty acids (PUFAs) with EPA levels ≥60% at a dosage of ≤1 g/d demonstrated therapeutic effects on the improvement of depression in a recent meta-analysis due to their anti-inflammatory properties.7 Inflammation has been shown to contribute to depressive disorders; both EPA and DHA have been shown to decrease the production of inflammatory cytokines TNF alpha, IL-1beta, IL-2, and IL-6 that are related to depression.7 According to a review, high levels of fish consumption and n-3 supplementation demonstrated protective effects against Alzheimer’s disease, decreased the incidence of Parkinson’s disease (PD) as well as depressive symptoms associated with PD, and improved the quality of life in patients with multiple sclerosis.17 Compared with the control group who received corn oil, test subjects with rheumatoid arthritis (RA) who supplemented 130 mg/kg/day of body weight of n-3 fatty acids for 30 weeks, had significant reductions in pain, morning stiffness, and tender joints.18
Dr. Berne’s Omega 3 Formula also includes vitamin E isomers (as DeltaGold® delta and gamma tocotrienols), which protect these fragile oils from oxidation and rancidity. Additionally, these fish oils are molecularly distilled and filtered to ensure purity and to maximize the removal of metals, pesticides, PCBs, and other contaminants.
References
1. Balch, P. A. (2011). Prescription for nutritional healing: a practical A-to-Z reference to drug-free remedies using vitamins, minerals, herbs & food supplements. London: Penguin.
2. Office of Dietary Supplements - Omega-3 Fatty Acids. (n.d.). Retrieved from https://ods.od.nih.gov/factsheets/ Omega3FattyAcids-HealthProfessional/.
3. Essential Fatty Acids. (2019, September 6). Retrieved from https://lpi.oregonstate.edu/mic/other-nutrients/ essential fatty-acids.
4. Bäck M. (2017). Omega-3 fatty acids in atherosclerosis and coronary artery disease. Future Science OA, 3(4), FSO236. DOI:10.4155/fsoa-2017-0067
5. Rutkofsky, I. H., Khan, A. S., Sahito, S., & Kumar, V. (2017). The psychoneuroimmunological role of omega-3 polyunsaturated fatty acids in major depressive disorder and bipolar disorder. Advances in Mind-Body Medicine, 31(3), 8-16.
6. Deacon, G., Kettle, C., Hayes, D., Dennis, C., & Tucci, J. (2017). Omega 3 polyunsaturated fatty acids and the treatment of depression. Critical Reviews in Food Science and Nutrition, 57(1), 212-223. DOI:10.1080/10408398.2013.876959
7. Liao, Y., Xie, B., Zhang, H., He, Q., Guo, L., Subramaniapillai, M., … Mclntyer, R. S. (2019). Efficacy of omega-3 PUFAs in depression: A meta-analysis. Translational Psychiatry, 9(1), 190. DOI:10.1038/s41398-019-0515-5
8. Pizzini, A., Lunger, L., Sonnweber, T., Weiss, G., & Tancevski, I. (2018). The role of omega-3 fatty acids in the setting of coronary artery disease and COPD: A review. Nutrients, 10(12), 1864. DOI:10.3390/nu10121864
9. Saccà, S., Cutolo, C., Ferrari, D., Corazza, P., & Traverso, C. (2018). The Eye, oxidative Damage and polyunsaturated fatty acids. Nutrients, 10(6), 668. DOI: 10.3390/nu10060668
10. Mallick, R., Basak, S., & Duttaroy, A.K. (2019). Docosahexaenoic acid,22:6n-3: Its roles in the structure and function of the brain. International Journal of Developmental Neuroscience, 79, 21–31. DOI: 10.1016/j.ijdevneu.2019.10.004
11. Kim, Y., Kim, H., & Kwon, O. (2019). Dietary intake of n-3 and n-6 polyunsaturated fatty acids in Korean toddlers 12- 24 months of age with comparison to the dietary recommendations. Nutrition research and practice, 13(4), 344–351. DOI:10.4162/nrp.2019.13.4.344
12. Perrin, M. T., Pawlak, R., Dean, L. L., Christis, A., & Friend, L. (2018). A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore
13. Fard, S. G., Wang, F., Sinclair, A. J. ,Elliott, G., & Turchini, G. M. (2018). How does high DHA fish oil affect health? A systematic review of evidence. Critical Reviews in Food Science and Nutrition, 59(11), 1684–1727. DOI: 10.1080/10408398.2018.1425978
14. Abdelhamid, A. S., Brown, T. J., Brainard, J. S., Biswas, P., Thorpe, G. C., Moore, H. J., … Hooper, L. (2018). Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. The Cochrane Database of Systematic Reviews, 7(7), CD003177. DOI:10.1002/14651858.CD003177.pub3
15. Piccinin, E., Cariello, M., Santis, S. D., Ducheix, S., Sabbà, C., Ntambi, J. M., & Moschetta, A. (2019). Role of oleic acid in the gut-liver axis: From diet to the regulation of its synthesis via stearoyl-CoA desaturase 1 (SCD1). Nutrients, 11(10), 2283. DOI: 10.3390/nu11102283
16. Kris-Etherton, P. M., Richter, C. K., Bowen, K. J., Skulas-Ray, A. C., Jackson, K. H., Petersen, K. S., & Harris, W. S. (2019). Recent clinical trials shed new light on the cardiovascular benefits of omega-3 fatty acids. Methodist DeBakey Cardiovascular Journal, 15(3), 171–178. DOI:10.14797/mdcj-15-3-171
17.Rodriguez-Guzman, E. (2019). Omega-3 polyunsaturated fatty acid supplementation as a potential protective factor or treatment for neurodegenerative diseases. Omega Fatty Acids in Brain and Neurological Health, 267–274. DOI: 10.1016/b978-0-12-815238-6.00017-1
18. Khanna, S., Jaiswal, K. S., & Gupta, B. (2017). Managing rheumatoid arthritis with dietary interventions. Frontiers in Nutrition, 4,52. DOI:10.3389/fnut.2017.00052
19. Veselinovic, M., Vasiljevic, D., Vucic, V., Arsic, A., Petrovic, S., Tomic-Lucic, A., …Jakovljevic, V. (2017). Clinical benefits of n-3 PUFA and ɤ-linolenic acid in patients with rheumatoid arthritis. Nutrients, 9(4), 325. DOI:10.3390/nu9040325
20. Nagatake, T., & Kunisawa, J. (2019). Emerging roles of metabolites of ω3 and ω6 essential fatty acids in the control of intestinal inflammation. International Immunology, 31(9), 569–577. DOI:10.1093/intimm/dxy086
