Factors that reduce vitamin C levels:

• Stress
• Smoking
• Illness
• Injury
• Birth control pills
• Estrogen use during menopause
• Certain medications, such as cortisone and aspirin
• Aging

Dr. Berne’s Vitamin C Formula is a proprietary blend of vitamin C and three unique bioflavonoids — naturally occurring plant substances found in brightly colored fruits and vegetables. This product is an effervescent, orange-flavored powder and contains no fructose or other unfavorable sweeteners. With a generous amount of vitamin C plus the three powerful bioflavonoids, Dr. Berne’s Vitamin C Formula simplifies getting optimal doses of these critical nutrients in a delicious-tasting beverage.

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin naturally present in some foods and used by many as a dietary supplement. Vitamin C is an essential vitamin, which means it cannot be made in the body and must be obtained from food or through supplements.

Vitamin C is a wonder nutrient, and is essential for immunity, bone maintenance, collagen formation (collagen is an essential component of connective tissue), and a broad range of other biological functions.

Bioflavonoids: Quercetin, Hesperidin and Rutin

Factors that reduce vitamin C levels:

• Stress
• Smoking
• Illness
• Injury
• Birth control pills
• Estrogen use during menopause
• Certain medications, such as cortisone and aspirin
• Aging

Some other facts on the ingredients:

Quercetin is a highly concentrated bioflavonoid found in citrus fruits, red wine, and tea. Sometimes called the ‘king of the flavonoids,’ this powerful antioxidant supports the immune system as well as a healthy inflammatory response.*

Hesperidin, another powerful but lesser-known bioflavonoid, can be found in oranges and grapefruits.

Rutin is found in asparagus, citrus fruits, and berries such as cranberries and mulberries.

Vitamin C and bioflavonoids are found together in nature because they work synergistically; for instance, oranges are rich in both vitamin C and the bioflavonoid, hesperidin. The inclusion of bioflavonoids in Dr. Berne’s Vitamin C Formula helps the body properly absorb and use vitamin C, and assists in preventing vitamin C from being destroyed by oxidation.

All three bioflavonoids in Dr. Berne’s Vitamin C Formula – quercetin, hesperiden and rutin – are noted for their protective, antioxidative and immune-supportive properties as well as their support for a healthy inflammatory response. They are also recognized for supporting heart health and their role in assisting to create a positive microbial balance in the body.*

Quercetin, hesperidin, and rutin, especially when paired with vitamin C, work together to protect and preserve the structure of blood capillaries, supporting blood vessel health.*

Recommended Use: As a dietary supplement take 4 grams (approx. one teaspoon) per day, or as directed by your health care practitioner.

Dr. Berne’s Vitamin C Formula is a unique effervescent, orange-flavored powder that contains vitamin C as ascorbic acid, calcium ascorbate, and magnesium ascorbate, along with the bioflavonoids quercetin, hesperidin, and rutin. These flavonoids improve the integrity and regulate the permeability of capillaries, while working in synergy with vitamin C to maintain collagen viability.

The bioflavonoids in C + Dr. Berne’s Vitamin C formula also help the body properly absorb and use vitamin C, prevent vitamin C from being destroyed by oxidation, help hemorrhages and ruptures in capillaries and connective tissue, and build a protective barrier against infection.* With a generous amount of vitamin C plus the three powerful bioflavonoids, Dr. Berne’s Vitamin C Formula simplifies getting optimal doses of these crucial vitamins in a convenient, delicious orange-flavored powder.

Vitamin C: The Wonder Nutrient_1-6

Other Ingredients: Tapioca dextrin, stevia leaf extract (Stevia rebaudiana), natural flavor, potassium bicarbonate, citric acid, silicon dioxide.

Perhaps more than any other nutrient, vitamin C (ascorbic acid) benefits an encyclopedic range of conditions.
The body needs adequate amounts of vitamin C for immunity, bone maintenance, collagen crosslinking,
enzymatic reactions, central nervous system function, and reducing inflammation, along with a broad range
of biological functions in order to maintain physiologic homeostasis._1-7. Recently, research has focused on the significant role that vitamin C plays in epigenetics, neurodegenerative diseases, and cancer._8-13 The level of ascorbic acid in the body naturally declines during the aging process._14-16 Other factors that reduce vitamin C levels include chronic stress (vitamin C helps support healthy adrenal function), smoking, illness, injury, and multiple medications such as oral contraceptives, estrogen replacement, corticosteroids, and aspirin._{1, 17-19}

Dr. Linus Pauling, who pioneered extensive research on vitamin C, believed optimal amounts exceed 2,000 mg daily.₁ C + BioFizzTM offers 2,569 mg of vitamin C in the combined form of ascorbic acid, calcium ascorbate, and magnesium ascorbate. Mineral ascorbates, which are buffered and therefore less acidic, can be beneficial for people who experience gastrointestinal problems such as abdominal pain and diarrhea with plain ascorbic acid.

Bioflavonoids Support Optimal Health

Bioflavonoids are the most abundant group of polyphenols. Scientists have identified several thousand bioflavonoids, which provide much of the flavor and color in fruits and vegetables. Research has focused on bioflavonoids’
impact on cardiovascular disease, cancer, and osteoporosis._55-58 As a group, they have demonstrated antioxidant, antidepressant, antibacterial, antiviral, anti-inflammatory, and anti-allergenic properties. ₂₀

Vitamin C Provides Three Well-Researched and Highly Beneficial Bioflavonoids

Quercetin is a highly concentrated bioflavonoid found in citrus fruits, red wine, and tea.₂₁ This powerful antioxidant reinforces the immune system, accelerates detoxifying-enzyme production, and may help reduce inflammation. A 2016 study concluded quercetin can reduce susceptibility to viral illnesses and protect the immune system against stress.₂₂ Quercetin may also provide valuable support in allergies, heart disease, hypertension, and cancer._23-27

Hesperidin, another powerful but lesser-known bioflavonoid, can be found in oranges and grapefruit. Studies show hesperidin, combined with vitamin C, offers anti-inflammatory and vasoprotective benefits. Hesperidin deficiencies can result in abnormal capillary leakiness and pain in the extremities that creates aches, weakness, and nighttime leg cramps._28-30

Rutin, found in apples, buckwheat, and other plants, is a potent anti-inflammatory flavonoid that helps to protect blood vessels, improve circulation, and prevent blood clots._31-33 Studies demonstrate that rutin can significantly reduce leg swelling, relieve leg pain, and reduce leg cramps, heaviness, and itching.₃₄ Rutin's antioxidant properties have been shown to be cardioprotective and boost heart health, relieve arthritis symptoms, protect against metabolic diseases, fight cancer, promote brain health and protect against brain injury, as well as attenuate gut dysbiosis and ameliorate renal fibrosis._{32, 35-51}

Bioflavonoids and Vitamin C Make a Powerful Nutrient Team _20-23

Bioflavonoids work synergistically with vitamin C.₅₂ For example, bioflavonoids and vitamin C work together to protect and preserve the structure of blood capillaries.₅₃ Bioflavonoids also protect the vitamin itself by inhibiting the breakdown of ascorbic acid and by preventing oxidation.₂₀ Nature often combines vitamin C and bioflavonoids, since they work synergistically. For instance, oranges are rich in vitamin C and hesperidin, which when combined, boost antioxidant protection.₅₄ However, supplementation is often necessary to obtain these bioflavonoids in therapeutic doses.