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Dr. Berne's Whole Health Support

Dr. Berne’s Curcumin

$35.00

Dr. Berne’s Curcumin is a highly bioavailable curcuminoid formulation. It contains a unique combination of three bioactive, health-promoting curcuminoids: curcumin, bisdemethoxycurcumin and desmethoxycurcumin, along with turmeric oil. The three curcuminoids are the strongest, most protective, and best-researched constituents of the turmeric root.

Dr. Berne’s Curcumin is a highly bioavailable formulation containing a unique combination of three health-promoting compounds known as "curcuminoids", which are derived from turmeric root: namely, curcumin, bisdemethoxy curcumin, and demethoxy curcumin. This comprehensive product also contains turmeric oil.
Turmeric is a bright yellow-orange spice popular as the main ingredient in Indian curry powders, and its high concentration of curcumin underlies the centuries-old use of this root in Ayurveda, traditional Indian medicine. The three curcuminoids in this product are the strongest, most protective and best researched constituents of turmeric root.

Naturally occurring turmeric root powder contains only 5-7% curcumin, while the blend in Dr. Berne’s Curcumin is formulated to contain 70% curcumin (as part of a total of 95% curcuminoids). Thus, this product provides a much higher concentration of the active compounds than would typically be obtainable from food alone.

BENEFITS

Eye Health: Curcumin has been shown to reduce inflammation, oxidative stress, and angiogenesis. It is effective at supporting eye health. Studies have shown that the influence of curcumin on eye diseases, such as glaucoma, cataract, age-related macular degeneration, diabetic retinopathy, corneal neovascularization, corneal wound healing, dry eye disease, conjunctivitis, pterygium, anterior uveitis are reported. The analysis of a number of clinical and preclinical investigations indicates that curcumin may be used as a therapeutic agent in the treatment of various eye disorders. Source: https://pubmed.ncbi.nlm.nih.gov/31530988/

Healthy Inflammatory Response – Like other “warming spices,” such as ginger, cinnamon, and cayenne, turmeric’s complement of curcuminoids helps to support a healthy inflammatory response in the body.

Immune Support – A wealth of scientific research supports the benefits of curcuminoid compounds for assisting with a healthy immune system, along with its ability to support the body’s natural defense against bacteria.

Antioxidant Properties – Curcumin is known to be a powerful antioxidant. Dr. Berne’s Curcumin is unique in that it increases levels of a major metabolite of curcumin, known as “tetrahydrocurcumin,” which has antioxidant effects greater than those of curcumin alone. 

Recommended Use: Take 1 softgel per day with a meal

ALL SALES ARE FINAL - SORRY NO RETURNS OR REFUNDS

 *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Ingredients

Current Research on Curcumin

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  3. Lai CS, Wu JC, Yu SF, Badmaev V, Nagabhushanam K, Ho CT, Pan MH. Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis. Mol Nutr Food Res. 2011 Dec;55(12):1819-28.

  4. Okada K, Wangpoengtrakul C, Tanaka T, Toyokuni S, Uchida K, Osawa T. Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice. J Nutr. 2001 Aug;131(8):2090-5.

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  8. Swarnakar S, Ganguly K.Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer. J Biol Chem. 2005 Mar 11;280(10):9409-15. Epub 2004 Dec 22.

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  33. Kim SY, Jung SH. Kim HS. Curcumin is a potent broad spectrum inhibitor of matrix metalloproteinase gene expression in human astroglioma cells. Biochem Biophys Res Commun. 2005 Nov 18;337(2):510-6. Epub 2005 Sep 21.

  34. Danilenko M, Studzinski GP.. Enhancement by other compounds of the anti-cancer activity of vitamin D(3) and its analogs. Exp Cell Res. 2004 Aug 15;298(2):339-58.

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    Carcinogenesis 1999;20:445-51.

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  38. Miquel J, Bernd A, The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review. Arch Gerontol Geriatr. 2002 Feb;34(1):37-46.

  39. Deeb D, Xu YX, Jiang H, et al. Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. Mol Cancer Ther 2003;2:95-103.

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  41. Shah BH, Nawaz Z, Pertani SA. Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca2+ signaling. Biochem Pharmacol 1999;58:1167-72.

  42. Thamlikitkul V, Bunyapraphatsara N, Dechatiwongse T, et al. Randomized double blind study of Curcuma domestica Val. for dyspepsia. J Med Assoc Thai 1989;72:613-20.

  43. Rasyid A, Rahman AR, Jaalam K, Lelo A. Effect of different curcumin dosages on human gall bladder. Asia Pac J Clin Nutr 2002;11:314-8.

  44. Leu TH, Maa MC.The molecular mechanisms for the antitumorigenic effect of curcumin. Curr Med Chem Anti-Canc Agents. 2002 May;2(3):357-70.

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  47. Thapliyal R, Maru GB. Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem Toxicol. 2001 Jun;39(6):541-7.

  48. Lal B, Kapoor AK, Asthana OP, et al. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res 1999;13:318-22.

  49. Takada Y, Bhardwaj A, Potdar P, Aggarwal BB. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxy genase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene 2004 Oct 18.

  50. Cole GM, Lim GP, Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions. Neurobiol Aging. 2005 Oct 30; [Epub ahead of print]

  51. Wang Q, Sun AY, Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. J Neurosci Res. 2005 Oct 1;82(1):138-48.

  52. Chan MM, Fong D. Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents. J Cell Physiol. 2003 Jan;194(1):63-70.

  53. Zheng L, Tong Q. Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms. J Huazhong Univ Sci Technolog Med Sci. 2004;24(1):55-8.

  54. Rajakrishnan V, Viswanathan P Neuroprotective role of curcumin from curcuma longa on ethanol-induced brain damage. Phytother Res. 1999 Nov;13(7):571-4.

  55. Rajakrishnan V, Jayadeep A. Changes in the prostaglandin levels in alcohol toxicity: effect of curcumin and N-acetylcysteine. J Nutr Biochem. 2000 Oct;11(10):509-14

  56. Satoskar RR, Shah SJ. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. Int J Clin Pharmacol Ther Toxicol.1986 Dec;24(12):651-4.

  57. Baum L, Ng A. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J Alzheimers Dis. 2004 Aug;6(4):367-77.

  58. Rajakrishnan V, Jayadeep A. Changes in the prostaglandin levels in alcohol toxicity: effect of curcumin and N-acetylcysteine. J Nutr Biochem. 2000 Oct;11(10):509-14

  59. Soni KB, Rajan A. Reversal of aflatoxin induced liver damage by turmeric and curcumin. Cancer Lett. 1992 Sep 30;66(2):115-21.

  60. Schulze-Tanzil G. Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes. Ann N Y Acad Sci. 2004
    Dec;1030:578-86.

Dr. Berne’s Curcumin

$35.00
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JR
15/11/2022
Josephine R.
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i love dr sam

his short videos are most helpful!!!